CortiSync is built on 300 mg of Sensoril ashwagandha plus six other ingredients. We review the stress and cortisol evidence, what it can't claim about testosterone and the cautions.
Its main ingredient has some support. CortiSync contains 300 mg of Sensoril ashwagandha per serving (not KSM-66), and Sensoril lowered stress scores and cortisol more than placebo in an 8-week, maker-funded trial at 125 to 500 mg a night. CortiSync itself has never been tested, it has no evidence for raising testosterone, and most of its other ingredients are at low or unstudied doses.
Per a published label listing (2 capsules): Sensoril ashwagandha 300 mg, lemon balm 150 mg, lychee fruit extract 120 mg, L-theanine 100 mg, holy basil 100 mg, magnolia bark 100 mg and Rhodiola rosea 50 mg. Every dose is listed and there is no proprietary blend; we could not confirm the label on the official site.
In a 2024 trial funded by Sensoril's maker, 98 stressed adults took 125, 250 or 500 mg of Sensoril nightly or placebo for 8 weeks. All three doses lowered perceived stress and plasma cortisol more than placebo, so CortiSync's 300 mg is within the tested range. Rhodiola's trials for stress-related fatigue are small and contradictory and used roughly 100 to 576 mg a day, versus 50 mg here. We couldn't match the other ingredients' doses to solid human trials for cortisol.
Chronic stress and high cortisol are linked with lower testosterone, but the idea of a simple "cortisol steal" of shared building blocks is an oversimplification. Sensoril has no testosterone trials, and CortiSync hasn't been tested for effects on testosterone. If testosterone is your main goal, see our Testosil review, our top pick among testosterone-support formulas.
Ashwagandha has been linked to rare liver injury and can raise thyroid hormone levels. Several ingredients can cause drowsiness, so take care with sedatives, sleep medicines, alcohol and driving. Rhodiola may interact with antidepressants and blood pressure medicines. CortiSync is not for pregnancy or breastfeeding.