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Does VigRX Plus Actually Work? The Clinical Evidence
WellnessChecked Editorial · October 2026
Does VigRX Plus Actually Work? The Clinical Evidence
VigRX Plus has one small published placebo-controlled trial (2012). We review what it found, how today's formula differs, the ingredients, cautions and the guarantee.
⚡ Quick AnswerLast Reviewed: October 2026
It may help some men with mild erection problems, but the evidence is limited. In VigRX Plus's one published trial, 75 men with mild to moderate erectile dysfunction finished 12 weeks; erectile function scores rose by about 9 points on VigRX Plus versus under 1 point on placebo. The trial was small, its funding isn't stated, and it tested an older, higher-dose formula. VigRX Plus is our top pick among male sexual-health supplements and comes with a 67-day guarantee. VigRX Plus is not a treatment for erectile dysfunction; see a doctor about persistent symptoms.
The Published Clinical Trial
The trial (Shah et al., 2012) enrolled 78 men aged 25 to 50 with mild to moderate erectile dysfunction at clinics in India; 75 completed (39 on VigRX Plus, 36 on placebo). Over 12 weeks, the IIEF erectile function score rose by an average of 9 points on VigRX Plus versus 0.61 on placebo, and the authors reported gains in desire, orgasm and satisfaction. Side effects were similar in both groups and mostly mild.
Keep the limits in mind. It's one small, short trial that hasn't been repeated by an independent team. The placebo response was unusually small. It tested an 11-ingredient formula at 2 capsules twice a day, while today's label lists 8 ingredients at 1 pill twice a day. Older versions of this page cited a different paper; the citation above is the correct one.
Key Ingredients
The official site (October 2026) lists eight ingredients; amounts aren't shown on the sales page:
Asian red ginseng: a handful of small ED trials, pooled evidence described as suggestive but low quality
Damiana, muira puama and catuaba bark: mainly traditional use and small uncontrolled studies
Ginkgo biloba: may raise bleeding risk with blood thinners
Hawthorn berry and saw palmetto: no meaningful evidence for sexual function
Bioperine (black pepper extract): can affect how the body processes some drugs
Tribulus, Cuscuta and epimedium were in the trial formula but are not on the current list.
Our Verdict
VigRX Plus may suit healthy men with mild erection concerns who want a herbal product with at least one published placebo-controlled trial behind it. Expectations should be modest. Anyone on blood thinners, diabetes or heart medicines should check with a doctor first, and persistent erection problems can be an early sign of heart disease, so they're worth raising with a doctor. Our VigRX Plus legitimacy check covers the company and the refund policy in more detail.
It has one small published placebo-controlled trial (2012) in which erectile function scores improved more than on placebo over 12 weeks. That trial hasn't been repeated independently and tested an older, higher-dose formula, so expect modest results at best.
The trial measured results at 12 weeks. The company suggests trying two containers over 60 days, and returned containers must reach its warehouse within 67 days of delivery to qualify for a refund. To keep the refund option, decide by about day 55 so returns arrive within 67 days of delivery.
In its trial, side effects were similar to placebo and mostly mild. Ginkgo and ginseng can affect bleeding and blood sugar, and hawthorn can interact with heart and blood pressure medicines, nitrates and ED drugs. Check with your doctor if you take prescription medication or have surgery planned.
Buy from the official site. The guarantee page doesn't say it covers third-party purchases, and counterfeits containing hidden sildenafil and tadalafil have been found. See where to buy VigRX Plus.
It's our top pick among male sexual-health supplements, mainly because it has a published placebo-controlled trial of the product, which is rare in this category. That evidence is still limited, so we don't present it as a sure thing.
Disclaimer: For informational purposes only. All products are dietary supplements — not medicines. Not intended to diagnose, treat, cure or prevent any disease. These statements have not been evaluated by the FDA. Individual results may vary. Always consult a qualified healthcare professional. We earn affiliate commissions via links on this page. Full disclaimer →
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