Written by the WellnessChecked Editorial Team. We checked the formula, the guarantee terms and the published research on its ingredients.
✍️ WellnessChecked Editorial Team✅ Sources listed on this page
Citrulline + arginine
Best for
No product trial
Evidence
67-Day
Guarantee (reported)
Scroll down to read our full analysis, including ingredient breakdown, pros & cons, and where to buy safely ↓
📋 Editorial & Affiliate Disclosure: This review was written by the WellnessChecked editorial team. We only cover products from brands we have affiliate relationships with, so our top picks are the best of the products we cover, not of every product on the market. We earn a commission if you purchase through our links — paid by the manufacturer at no extra cost to you. We aim to describe every product accurately, including its limits. Read about our methodology → | Full disclaimer →
⚡ Quick AnswerLast Reviewed: October 2026
VigRX Nitric Oxide Support is a dietary supplement that combines L-citrulline and L-arginine, two amino acids the body uses to make nitric oxide. Both have some human evidence for mild erection problems at gram doses, but this product's doses aren't disclosed and the product itself hasn't been studied. We couldn't confirm the "NO3-T" nitrate our earlier review described. A third-party review reports a 67-day money-back guarantee. It is not a treatment for erectile dysfunction; see a doctor about persistent symptoms.
📋 Quick Reference — VigRX Nitric Oxide
Product Type
Amino acid capsule
Best For
Citrulline + arginine formula
Guarantee
67-day (unverified)
Evidence
Ingredient studies only
Category
Men's Health
Last Reviewed
October 2026
Our Verdict: Is VigRX Nitric Oxide Worth It?
💬 WellnessChecked Editorial Verdict
VigRX Nitric Oxide Support may suit healthy men who want an L-arginine and L-citrulline product, two amino acids with some evidence for mild erection problems at gram doses. Its doses aren't disclosed and the product itself hasn't been studied, and anyone on nitrates, ED drugs or blood pressure medicines should check with a doctor first.
In this review we go through what's in VigRX Nitric Oxide, what the research on its ingredients shows, the side effects and interactions, and the guarantee. Read the full analysis below before making a decision.
VigRX Nitric Oxide at a Glance
Ingredients
L-citrulline and L-arginine. Doses not disclosed.
Evidence
No study of the product. L-arginine has a meta-analysis for mild to moderate ED at 1.5–5 g a day; L-citrulline has one small pilot study.
Transparency
Maker named, but doses and the official ingredient list couldn't be checked.
Safety
Usually mild stomach effects. Can lower blood pressure, especially with nitrates, ED drugs or blood pressure medicines.
Value
Price not verified (October 2026).
We compare products on ingredients and doses, published evidence, transparency and guarantee terms, safety and value. How we review →
What Is VigRX Nitric Oxide?
VigRX Nitric Oxide Support is a VigRX-brand capsule from Leading Edge Health. A third-party review describes it as a "patented mixture of L-citrulline and L-arginine", with no doses or serving size shown. We couldn't check the official ingredient list (the old product site now redirects to vigrx.com), and we couldn't confirm the "NO3-T" nitrate our earlier review described. The body uses both amino acids to make nitric oxide, which helps blood vessels relax.
*Dietary supplement. Not intended to diagnose, treat, cure or prevent any disease. Statements not evaluated by the FDA.
Active Ingredients — Full Scientific Breakdown
What each listed ingredient is and what human studies have looked at. Where the maker doesn't disclose doses, we can't say whether they match the studies:
L-CitrullineNitric Oxide Precursor
The body converts it to L-arginine, and it can raise blood arginine levels more than arginine itself. One small pilot study (24 men with mild ED, 1.5 g a day for a month, single-blind) found 50% reported harder erections vs 8% on placebo. This product's dose isn't disclosed.
L-ArginineNitric Oxide Precursor
Used by the body to make nitric oxide. A 2019 meta-analysis (10 trials, 540 men) suggested benefit for mild to moderate ED at 1,500–5,000 mg a day. We can't tell whether this product reaches those amounts.
Our earlier review listed a patented "NO3-T" nitrate. We couldn't confirm it in the current formula, so we've removed it.
📋 Our Editorial Concerns
In the interest of balance, here are the limitations of VigRX Nitric Oxide that we think buyers should know:
→Doses aren't disclosed, so it may not reach the amounts used in studies
→No study of the product itself
→Can lower blood pressure, especially with nitrates, ED drugs or blood pressure medicines
→Claims about a patented nitrate and "sustained release" couldn't be confirmed
Results Timeline: What to Expect
What ingredient studies measured, and what isn't known. Individual results vary:
1
First Days: No Product Data
No study of this product measured blood flow or erections, so there's no reliable data on how quickly anything changes.
2
About 1 Month: What the Pilot Study Measured
The L-citrulline pilot study ran one month at 1.5 g a day, and arginine trials ran for weeks. This product's doses aren't disclosed, so results may differ.
⚠️ Important: Supplement response varies. These timings describe ingredient studies, not this product, and are not a promise. A third-party review reports a 67-day money-back guarantee; check the terms before you buy.
🔬 What the Evidence Actually Shows
Trial of the product itself: None published that we could find.
Ingredients: L-arginine: a 2019 meta-analysis (10 trials, 540 men) suggested benefit for mild to moderate ED at 1,500–5,000 mg a day. L-citrulline: one small pilot study (24 men, 1.5 g a day for a month) reported harder erections more often than placebo.
Doses on the label: Not disclosed, so we can't tell whether it reaches studied amounts.
Guarantee: 67-day money-back guarantee, per a third-party review. Exact conditions (empty containers, shipping, limits) not verified.
✓Uses L-arginine and L-citrulline, which have some human evidence for mild ED
✓Simple, stimulant-free formula
✓Money-back guarantee advertised
✗ Considerations
✗Doses not disclosed, so it may not reach studied amounts
✗No study of the product itself
✗Can interact with nitrates, ED drugs and blood pressure medicines
✗Patented-nitrate and 'sustained release' claims could not be confirmed
⚠️ Who Should NOT Take VigRX Nitric Oxide
✗Anyone taking nitrates (such as nitroglycerin), ED drugs (sildenafil, tadalafil) or blood pressure medicines, unless a doctor says it's OK
✗Anyone who has recently had a heart attack
✗Anyone on diabetes medicines, blood thinners or potassium-sparing diuretics without a doctor's OK
✗Pregnant or breastfeeding women, and anyone under 18
✗Anyone with persistent erection problems who hasn't seen a doctor (they can be an early sign of heart disease)
This list isn't complete. Check with a doctor or pharmacist before taking any supplement.
Is VigRX Nitric Oxide Safe?
VigRX Nitric Oxide itself has not been studied for safety in a published trial we could find. L-arginine and L-citrulline are usually well tolerated in studies, but L-arginine can lower blood pressure and interacts with several medicines.
✓ What We Know
L-arginine can cause nausea, bloating and diarrhea. Mayo Clinic advises against it after a recent heart attack, and it can interact with nitrates, ED drugs, blood pressure and diabetes medicines, blood thinners and potassium-sparing diuretics.
⚠️ Consult Your Doctor If:
● You take nitrates, ED drugs or blood pressure medicines
● You have heart disease or recently had a heart attack
● You take diabetes medicines, blood thinners or potassium-sparing diuretics
● You are pregnant or breastfeeding
● You are under 18 years of age
Where to Buy VigRX Nitric Oxide Safely
We suggest buying from the official website, so you can:
✓ Avoid unknown sellers, who may not be authorized
✓ Use the money-back guarantee (67 days per a third-party review; check the terms)
🛡️ 67-day guarantee reported (terms not verified) · Official seller
*Individual results vary. Not intended to diagnose, treat, cure or prevent any disease. These statements have not been evaluated by the FDA. Full disclaimer →
🛡️ Final Verdict: VigRX Nitric Oxide
VigRX Nitric Oxide Support may suit healthy men who want an L-arginine and L-citrulline product, two amino acids with some evidence for mild erection problems at gram doses. Its doses aren't disclosed and the product itself hasn't been studied, and anyone on nitrates, ED drugs or blood pressure medicines should check with a doctor first.
Best for: healthy men with mild erection concerns who want a simple, stimulant-free amino acid formula.
Not for: anyone on nitrates, ED drugs or blood pressure medicines, anyone recovering from a heart attack, or anyone who wants a product with its own published study.
🛡️ 67-day money-back guarantee reported (check the terms)
*These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure or prevent any disease. Individual results may vary. Full disclaimer →
Not necessarily. Oral L-arginine is partly broken down before it reaches the bloodstream, while L-citrulline is converted to arginine in the body, which can raise blood arginine levels more than arginine itself. Whether that improves erections at this product's dose is unknown, because the doses aren't disclosed.
The product hasn't been studied for safety. L-arginine can cause nausea, bloating or diarrhea and can lower blood pressure, especially with nitrates, ED drugs or blood pressure medicines. It also interacts with diabetes medicines, blood thinners and potassium-sparing diuretics, so check with your doctor if you take prescription medication.
From the official VigRX website or an authorized seller; unknown sellers may not be authorized. A third-party review reports a 67-day money-back guarantee; the terms we read don't say they cover third-party purchases, so buy direct if you want to rely on it.
Anyone on nitrates, ED drugs or blood pressure medicines, anyone who has recently had a heart attack, pregnant or breastfeeding women and anyone under 18 should not take it without a doctor's OK. Persistent erection problems can be an early sign of heart disease, so they're worth raising with a doctor.
Also Consider
Other supplements in Men's Health you may want to compare:
Please note: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any supplement. Individual results vary. *Not evaluated by the FDA. Not intended to diagnose, treat, cure or prevent any disease.
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